Welcome to the Cathedral of St. Mary of the Annunciation Roman Catholic Church!

We believe our parish is a sacred place where human and divine meet, where people of all ages gather to grow in the knowledge and love of our Lord Jesus Christ. We encourage you to be a part of our parish family as we receive spiritual nourishment, guidance, inspiration and strength.  We ask you to join in our spiritual journey where we share each other's joys and sorrows, help those who are struggling and hurt. We invite you to make new friends, to reach out and invite others to be a part of our community of believers.If it's been awhile since you've been to church, click here for more information. We invite you to explore our website, and check out our Facebook page and most importantly, come to Mass!

Bishop's Letter Welcome Back to Mass!  March 2021

St Mary Cathedral Mass Live Stream Sunday Mass  Mass is live streamed at 8:30 AM on Sunday.





Mass Times

Saturday: 4:30 pm

Sunday: 7:00 am, 8:30 am,
10:30 am

Tuesday: 8:00 am, 5:15 pm

Weekdays:  6:00 am, 8:00 am


Saturdays 3:15-4:15 PM

Tuesdays 4:30-5:00 PM

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Perpetual Help Devotion video

Praying Matters





Parish News

Keep up with our parish family here by viewing news announcements, activities, pictures and videos.

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Online Giving

Our parish has set up the ability to tithe and make donations electronically.  It’s easy to set up with our safe and effective offertory system.

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Get Involved

Get involved in our parish with liturgical ministries, church activities, and membership.

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Faith is a journey.

We, as Catholic Christians joyfully worship God in faith. We learn, live and share our faith with others, with Mary as our Model. We listen to the Holy Spirit and use our gifts and talents as stewards to love and serve God and one another on our faith journey.


2021 Marian Conference Immaculate Conception Church in Jackson will host the 2021 Marian Conference August 13/14, 2021. Mark your calendars for this opportunity for spiritual growth. Call Immaculate Conception Parish office to register, 573-243-3182.
Fr. Connor Danstrom has the right idea.  Sometimes instead of looking for excuses, just do it, just go to Mass.  Read here his memories of growing up and being encouraged to attend Sunday Mass.   Just Do It
Welcome home youth and Deacon Peirano from Steubenville 2021!
Congratulations to our new officers for the Parish  Council of Catholic Women at St. Mary Cathedral. Jacque Aden, President, Carolyn Spinner, Vice President, Pat Eftink, Treasurer, Imelda Nenninger, Secretary.
Congratulations to LifeHouse in Springfield for celebrating 100 babies born! Please help the LifeHouse Maternity home in Cape Girardeau being built by Catholic Charities. They need support to build this wonderful facility for women on the east side of our diocese in Cape Girardeau. You can click ...

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Upcoming Events

Daily Readings