Welcome to the Cathedral of St. Mary of the Annunciation Roman Catholic Church!

We believe our parish is a sacred place where human and divine meet, where people of all ages gather to grow in the knowledge and love of our Lord Jesus Christ. We encourage you to be a part of our parish family as we receive spiritual nourishment, guidance, inspiration and strength.  We ask you to join in our spiritual journey where we share each other's joys and sorrows, help those who are struggling and hurt. We invite you to make new friends, to reach out and invite others to be a part of our community of believers.If it's been awhile since you've been to church, click here for more information. We invite you to explore our website, and check out our Facebook page and most importantly, come to Mass!

Bishop's Letter June 17, 2020 Co-vid

Co-vid 19 Information concerning Mass

St Mary Cathedral Mass Live Stream Sunday Mass  Mass is live streamed at 8:30 AM on Sunday.





Mass Times

Saturday: 4:30 pm

(also a 6:00 PM temporarily during CoVid)

Sunday: 7:00 am, 8:30 am,
10:30 am

Tuesday: 8:00 am, 5:15 pm

Weekdays:  6:00 am, 8:00 am


Saturdays 3:15-4:15 PM

Tuesdays 4:30-5:00 PM

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Perpetual Help Devotion video

Praying Matters





Parish News

Keep up with our parish family here by viewing news announcements, activities, pictures and videos.

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Online Giving

Our parish has set up the ability to tithe and make donations electronically.  It’s easy to set up with our safe and effective offertory system.

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Get Involved

Get involved in our parish with liturgical ministries, church activities, and membership.

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Faith is a journey.

We, as Catholic Christians joyfully worship God in faith. We learn, live and share our faith with others, with Mary as our Model. We listen to the Holy Spirit and use our gifts and talents as stewards to love and serve God and one another on our faith journey.


Here is a wonderful resource for Lent this year, but they also have a monthly version.  Catholic resources to help teach your children and other family members about the faith.  They are called Catholic Family Crates.  See this website for more information:  Catholic Family Crate...

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Frequent Church Attendance during 2020 Helps Mental Health
On Veteran’s Day, November 11, the student body of St. Mary Cathedral School in Cape Girardeau participated in the blessing and dedication of the Veteran’s Memorial recently placed near the school gym doors.  Fr. Allan Saunders performed the blessing.  St. Mary’s parishio...

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The Works of Mercy Video What Are the Works of Mercy?
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Upcoming Events

Daily Readings