• Marian Conference at St. Mary Cathedral
  • Picnic!


Welcome to the Cathedral of St. Mary of the Annunciation Roman Catholic Church.

We believe our parish is a sacred place where human and divine meet, where people of all ages gather to grow in the knowledge and love of our Lord Jesus Christ. We encourage you to be a part of our parish family as we receive spiritual nourishment, guidance, inspiration and strength.  We ask you to join in our spiritual journey where we share each other's joys and sorrows, help those who are struggling and hurt. We invite you to make new friends, to reach out and invite others to be a part of our community of believers.

If it's been awhile since you've been to church, click here for more information. 

We invite you to explore our website, and check out our Facebook page and most importantly stop by and visit Jesus in church! You are always welcome!

For information concerning our website, please contact Lisa Simmons,, 573-335-9347.


Mass Times

Saturday: 4:00 pm, 5:30 pm

Sunday: 7:00 am, 8:30 am,
10:30 am

Tuesday: 8:00 am, 5:15 pm

Weekdays:  6:00 am, 8:00 am

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Parish News

Keep up with our parish family here by viewing news announcements, activities, pictures and videos.

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Online Giving

Our parish has set up the ability to tithe and make donations electronically.  It’s easy to set up with our safe and effective offertory system.

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Get Involved

Get involved in our parish with liturgical ministries, church activities, and membership.

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Faith is a journey.

We, as Catholic Christians joyfully worship God in faith. We learn, live and share our faith with others, with Mary as our Model. We listen to the Holy Spirit and use our gifts and talents as stewards to love and serve God and one another on our faith journey.


Mrs. Carol Strattman There will be a reception in honor of Carol Strattman, St. Mary Cathedral School Principal on Sunday, May 7th at 11:30 A.M. in the school cafeteria. Mrs. Strattman has touched the hearts of so many people in her time at St. Mary's and this is our chance to share our me...

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You are invited to the first Marian Conference at St. Mary Cathedral, 615 William Street in Cape Girardeau Mo. on April 28th and 29th.  The agenda for the conference will include 5 speakers, Mass, Adoration, Confession, the Rosary and spiritual resources. The Marian Conference will convene Frid...

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Hear the school kids sing at Mass this week! click the link below:     Friday, Sept. 23, 2016
Do you know of someone who might be interested in learning more about the Catholic Faith? RCIA classes will begin in September. Contact Jim or Linda at 573-335-9347.  
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Upcoming Events

Daily Readings

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